5-Amino-1MQ (NNMT Inhibitor)

Product Name: 5-Amino-1MQ
Chemical Name: 5-Amino-1-methylquinolinium
Molecular Formula: C₁₀H₁₁N₂⁺
Molecular Weight: 159.21 g/mol
Purity: ≥98% (HPLC)
Appearance: White to off-white crystalline powder
Solubility: Soluble in DMSO, ethanol, and water
Storage Conditions: Store at -20°C, protected from light and moisture
Shelf Life: 24 months when stored properly

Product Description

5-Amino-1MQ is a potent and selective small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that plays a critical role in cellular metabolism and energy homeostasis. By inhibiting NNMT activity, 5-Amino-1MQ increases intracellular NAD⁺ levels, a key coenzyme involved in mitochondrial function and fat oxidation.

Key Research Findings:

• Enhanced Fat Oxidation: Preclinical studies demonstrate that 5-Amino-1MQ promotes the breakdown of adipose tissue by increasing fatty acid oxidation

• Lean Muscle Preservation: Unlike many metabolic interventions, 5-Amino-1MQ helps maintain lean muscle mass during weight loss

• Improved Insulin Sensitivity: Research indicates potential benefits for glucose metabolism and insulin sensitivity

• Metabolic Regulation: Modulates key metabolic pathways involved in energy expenditure and fat storage

Applications:

• Metabolic health and obesity research

• Weight management mechanism studies

• Mitochondrial function investigation

• NAD⁺ metabolism research

Quality Assurance:

• Purity verified by HPLC analysis

• Certificate of Analysis provided with each batch

• Third-party testing available upon request

• Stable under recommended storage conditions

Packaging Options:

• Research quantities: 10mg, 50mg, 100mg

• Bulk quantities: Custom packaging available for research institutions and pharmaceutical manufacturers