Semaglutide (GLP-1 Receptor Agonist)

Product Name: Semaglutide API

CAS No.: 910463-68-2

Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉

Molecular Weight: 4113.58 g/mol

Purity: ≥99% (HPLC) — third-party verified

Appearance: White to off-white lyophilized powder

Solubility: Soluble in water and dilute acids

Form: Sterile lyophilized powder in vacuum-sealed vials

Storage: -20°C, protected from light and moisture

Shelf Life: 24 months under recommended storage conditions

Packaging Options: 10mg, 50mg, 100mg, 1g, 5g (bulk quantities available for qualified pharmaceutical manufacturers)

Product Description

Semaglutide is a long-acting GLP-1 (glucagon-like peptide-1) receptor agonist widely used in pharmaceutical research for type 2 diabetes and obesity. Its molecular structure includes modifications that extend its half-life to approximately 7 days, enabling once-weekly dosing in clinical applications.

Mechanism of Action:

• Binds to and activates GLP-1 receptors in the pancreas, brain, and other tissues

• Enhances glucose-dependent insulin secretion

• Suppresses glucagon release

• Slows gastric emptying

• Reduces appetite and food intake through central nervous system effects

Clinical Research Profile:
In published studies, Semaglutide has demonstrated:

• 15–20% body weight reduction over 68 weeks at the 2.4 mg dose

• Significant HbA1c reduction in type 2 diabetes patients

• Cardiovascular protective effects in outcomes trials

• Established safety profile with manageable gastrointestinal effects

Research Applications:

• Type 2 diabetes and obesity research

• GLP-1 receptor mechanism studies

• Cardiovascular outcomes research

• Combination therapy investigations

• Reference standard for analytical method development

Quality Assurance

• Manufactured in alignment with GMP guidelines

• Purity verified by HPLC (≥99%)

• Mass spectrometry confirmation for molecular identity

• Certificate of Analysis (CoA) provided with each shipment

• Residual solvent analysis available upon request

• Stability data available for qualified research institutions

Important Notice

All peptide products supplied by Jintai Sheng are intended for verified pharmaceutical manufacturers and research institutions only. We do not sell to individual consumers. This product is for research and manufacturing use only—not for human or veterinary use.

Need complete technical specifications? For detailed information including residual solvent analysis, mass spectrometry data, and stability studies, please contact our commercial representatives. We typically respond within 24 hours on business days.